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Identification of predominant GNPTAB gene mutations in Eastern Chinese patients with mucolipidosis II/III and a prenatal diagnosis of mucolipidosis II

Mucolipidosis II α/β, mucolipidosis III α/β, and mucolipidosis III γ are autosomal recessive disorders belonging to the family of lysosomal storage disorders caused by deficiency of the UDP-N-acetylglucosamine, a lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-phosphotransferase) l...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Wang, Yu, Ye, Jun, Qiu, Wen-juan, Han, Lian-shu, Gao, Xiao-lan, Liang, Li-li, Gu, Xue-fan, Zhang, Hui-wen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329779/
https://ncbi.nlm.nih.gov/pubmed/29872134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0023-9
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