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Antitumor effect of axitinib combined with dopamine and PK-PD modeling in the treatment of human breast cancer xenograft

Rising evidence has shown the development of resistance to vascular endothelial growth factor receptor (VEGFR) inhibitors in the practices of cancer therapy. It is reported that the efficacy of axitinib (AX), a VEGFR inhibitor, is limited in the treatment of breast cancer as a single agent or in com...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Ma, Yuan-heng, Wang, Si-yuan, Ren, Yu-peng, Li, Jian, Guo, Ting-jie, Lu, Wei, Zhou, Tian-yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329750/
https://ncbi.nlm.nih.gov/pubmed/29773888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0006-x
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