Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity

GWAS identified variants associated with birth weight (BW), childhood obesity (CO) and childhood BMI (CBMI), and placenta is a critical organ for fetal development and postnatal health. We examined the role of placental transcriptome and eQTLs in mediating the genetic causes for BW, CO and CBMI, and...

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Vydáno v:PLoS Genet
Hlavní autoři: Peng, Shouneng, Deyssenroth, Maya A., Di Narzo, Antonio F., Cheng, Haoxiang, Zhang, Zhongyang, Lambertini, Luca, Ruusalepp, Arno, Kovacic, Jason C., Bjorkegren, Johan L. M., Marsit, Carmen J., Chen, Jia, Hao, Ke
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329610/
https://ncbi.nlm.nih.gov/pubmed/30596636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007799
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