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Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity

GWAS identified variants associated with birth weight (BW), childhood obesity (CO) and childhood BMI (CBMI), and placenta is a critical organ for fetal development and postnatal health. We examined the role of placental transcriptome and eQTLs in mediating the genetic causes for BW, CO and CBMI, and...

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Publicado en:PLoS Genet
Autores principales: Peng, Shouneng, Deyssenroth, Maya A., Di Narzo, Antonio F., Cheng, Haoxiang, Zhang, Zhongyang, Lambertini, Luca, Ruusalepp, Arno, Kovacic, Jason C., Bjorkegren, Johan L. M., Marsit, Carmen J., Chen, Jia, Hao, Ke
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329610/
https://ncbi.nlm.nih.gov/pubmed/30596636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007799
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