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Improved DNA extraction technique from clot for the diagnosis of Chagas disease

BACKGROUND: The detection of Trypanosoma cruzi genetic material in clinical samples is considered an important diagnostic tool for Chagas disease. We have previously demonstrated that PCR using clot samples yields greater sensitivity than either buffy coat or whole blood samples. However, phenol-chl...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Mayta, Holger, Romero, Yomara K., Pando, Alejandra, Verastegui, Manuela, Tinajeros, Freddy, Bozo, Ricardo, Henderson-Frost, Josephine, Colanzi, Rony, Flores, Jorge, Lerner, Richard, Bern, Caryn, Gilman, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329489/
https://ncbi.nlm.nih.gov/pubmed/30633743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007024
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