Druggable Oncogene Fusions in Invasive Mucinous Lung Adenocarcinoma

PURPOSE: To identify druggable oncogenic fusions in invasive mucinous adenocarcinoma (IMA) of the lung, a malignant type of lung adenocarcinoma in which KRAS mutations frequently occur. EXPERIMENTAL DESIGN: From an IMA cohort of 90 cases, consisting of 56 cases (62%) with KRAS mutations and 34 cases...

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Publicat a:Clin Cancer Res
Autors principals: Nakaoku, Takashi, Tsuta, Koji, Ichikawa, Hitoshi, Shiraishi, Kouya, Sakamoto, Hiromi, Enari, Masato, Furuta, Koh, Shimada, Yoko, Ogiwara, Hideaki, Watanabe, Shun-ichi, Nokihara, Hiroshi, Yasuda, Kazuki, Hiramoto, Masaki, Nammo, Takao, Ishigame, Teruhide, Schetter, Aaron J., Okayama, Hirokazu, Harris, Curtis C., Kim, Young Hak, Mishima, Michiaki, Yokota, Jun, Yoshida, Teruhiko, Kohno, Takashi
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329293/
https://ncbi.nlm.nih.gov/pubmed/24727320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0107
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