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Glucose transporter 1 critically controls microglial activation through facilitating glycolysis

BACKGROUND: Uncontrolled microglial activation contributes to the pathogenesis of various neurodegenerative diseases. Previous studies have shown that proinflammatory microglia are powered by glycolysis, which relays on high levels of glucose uptake. This study aimed to understand how glucose uptake...

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Bibliografiske detaljer
Udgivet i:Mol Neurodegener
Main Authors: Wang, Luxi, Pavlou, Sofia, Du, Xuan, Bhuckory, Mohajeet, Xu, Heping, Chen, Mei
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329071/
https://ncbi.nlm.nih.gov/pubmed/30634998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0305-9
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