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Ascorbic acid improves parthenogenetic embryo development through TET proteins in mice

The TET (Ten-Eleven Translocation) proteins catalyze the oxidation of 5mC (5-methylcytosine) to 5hmC (5-hydroxymethylcytosine) and play crucial roles in embryonic development. Ascorbic acid (Vc, Vitamin C) stimulates the expression of TET proteins, whereas DMOG (dimethyloxallyl glycine) inhibits TET...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Gao, Wei, Yu, Xianfeng, Hao, Jindong, Wang, Ling, Qi, Minghui, Han, Liang, Lin, Chao, Wang, Dongxu
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328890/
https://ncbi.nlm.nih.gov/pubmed/30567727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181730
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