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MCPIP1 regulates the sensitivity of pancreatic beta-cells to cytokine toxicity
The autoimmune-mediated beta-cell death in type 1 diabetes (T1DM) is associated with local inflammation (insulitis). We examined the role of MCPIP1 (monocyte chemotactic protein–induced protein 1), a novel cytokine-induced antiinflammatory protein, in this process. Basal MCPIP1 expression was lower...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328635/ https://ncbi.nlm.nih.gov/pubmed/30631045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1268-4 |
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