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Ca(2+)-activated Cl(−) channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration

The Ca(2+)-activated Cl(−) channel (CaCC) TMEM16A/Anoctamin 1 (ANO1) is expressed in gastrointestinal epithelia and smooth muscle cells where it mediates secretion and intestinal motility. However, ANO1 Cl(−) conductance has never been reported to play a role in skeletal muscle. Here we show that AN...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Dayal, Anamika, Ng, Shu Fun J., Grabner, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328546/
https://ncbi.nlm.nih.gov/pubmed/30631052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07918-z
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