Homophilic CD44 interactions mediate tumor cell aggregation and polyclonal metastasis in patient-derived breast cancer models

Circulating tumor cells (CTCs) seed cancer metastases; however, the underlying cellular and molecular mechanisms remain unclear. CTC clusters were less frequently detected but more metastatic than single CTCs of triple negative breast cancer patients and representative patient-derived-xenograft (PDX...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Discov
Main Authors: Liu, Xia, Taftaf, Rokana, Kawaguchi, Madoka, Chang, Ya-Fang, Chen, Wenjing, Entenberg, David, Zhang, Youbin, Gerratana, Lorenzo, Huang, Simo, Patel, Dhwani B., Tsui, Elizabeth, Adorno-Cruz, Valery, Chirieleison, Steven M., Cao, Yue, Harney, Allison S., Patel, Shivani, Patsialou, Antonia, Shen, Yang, Avril, Stefanie, Gilmore, Hannah L., Lathia, Justin D., Abbott, Derek W., Cristofanilli, Massimo, Condeelis, John S., Liu, Huiping
פורמט: Artigo
שפה:Inglês
יצא לאור: 2018
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328322/
https://ncbi.nlm.nih.gov/pubmed/30361447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-0065
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