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Prg4 prevents osteoarthritis induced by dominant-negative interference of TGF-ß signaling in mice
OBJECTIVE: Prg4, also known as Lubricin, acts as a joint/boundary lubricant. Prg4 has been used to prevent surgically induced osteoarthritis (OA) in mice. Surgically induced OA serves as a good model for post-traumatic OA but is not ideal for recapitulating age-related OA. Reduced expression of the...
Gorde:
| Argitaratua izan da: | PLoS One |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328116/ https://ncbi.nlm.nih.gov/pubmed/30629676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210601 |
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