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The Tuberin and Cyclin B1 complex functions as a novel G2/M sensor of serum conditions and Akt signaling

A great deal of ground breaking work has determined that the Tuberin and Hamartin Complex function as a negative regulator of protein synthesis and cell cycle progression through G1/S. This is largely attributed to the GTPase activity of Tuberin that indirectly inhibits the mammalian target of rapam...

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Foilsithe in:PLoS One
Main Authors: Fidalgo da Silva, Elizabeth, Botsford, Sabrina, Dare-Shih, Jessica, Hanna, Miranda A., Porter, Lisa A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328093/
https://ncbi.nlm.nih.gov/pubmed/30629673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210612
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