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CD4(+) T cells induce rejection of urothelial tumors after immune checkpoint blockade
Immune checkpoint blockade (ICB) provides clinical benefit to a minority of patients with urothelial carcinoma (UC). The role of CD4(+) T cells in ICB-induced antitumor activity is not well defined; however, CD4(+) T cells are speculated to play a supportive role in the development of CD8(+) T cells...
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| Gepubliceerd in: | JCI Insight |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328023/ https://ncbi.nlm.nih.gov/pubmed/30518683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121062 |
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