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Thioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches

The aim of the present study was to define the role of Trx and Grx on metabolic thiol redox regulation and identify their protein and metabolite targets. The hepatocarcinoma-derived HepG2 cell line under both normal and oxidative/nitrosative conditions by overexpression of NO synthase (NOS3) was use...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: López-Grueso, MJ, González-Ojeda, R, Requejo-Aguilar, R, McDonagh, B, Fuentes-Almagro, CA, Muntané, J., Bárcena, J.A., Padilla, CA
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327914/
https://ncbi.nlm.nih.gov/pubmed/30639960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.11.007
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