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Chikungunya-vesicular stomatitis chimeric virus targets and eliminates brain tumors
Vesicular stomatitis virus (VSV) shows potential for targeting and killing cancer cells, but can be dangerous in the brain due to its neurotropic glycoprotein. Here we test a chimeric virus in which the VSV glycoprotein is replaced with the Chikungunya polyprotein E3-E2-6K-E1 (VSVΔG-CHIKV). Control...
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| Published in: | Virology |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6327847/ https://ncbi.nlm.nih.gov/pubmed/30055515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.06.018 |
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