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Drug Targets for Heart Failure with Preserved Ejection Fraction: A Mechanistic Approach and Review of Contemporary Clinical Trials

Heart failure with preserved ejection fraction (HFpEF) accounts for over half of prevalent heart failure (HF) worldwide, and prognosis after hospitalization for HFpEF remains poor. Due, at least in part, to the heterogeneous nature of HFpEF, drug development has proved immensely challenging. Current...

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Detalhes bibliográficos
Publicado no:Annu Rev Pharmacol Toxicol
Main Authors: Patel, Ravi B., Shah, Sanjiv J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327844/
https://ncbi.nlm.nih.gov/pubmed/30296895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010818-021136
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