Fusobacterium nucleatum promotes chemoresistance to 5-fluorouracil by upregulation of BIRC3 expression in colorectal cancer

BACKGROUND: Emerging evidence suggests a potential relationship between gut microbiota and the host response to chemotherapeutic drugs including 5-fluorouracil (5-Fu). Fusobacterium nucleatum (Fn) has been linked to the initiation and progression of colorectal cancer (CRC). Unfortunately, little was...

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Dades bibliogràfiques
Publicat a:J Exp Clin Cancer Res
Autors principals: Zhang, Sheng, Yang, Yongzhi, Weng, Wenhao, Guo, Bomin, Cai, Guoxiang, Ma, Yanlei, Cai, Sanjun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327560/
https://ncbi.nlm.nih.gov/pubmed/30630498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0985-y
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