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Estimating the clinical cost of drug development for orphan versus non-orphan drugs

BACKGROUND: High orphan drug prices have gained the attention of payers and policy makers. These prices may reflect the need to recoup the cost of drug development from a small patient pool. However, estimates of the cost of orphan drug development are sparse. METHODS: Using publicly available data,...

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Dettagli Bibliografici
Pubblicato in:Orphanet J Rare Dis
Autori principali: Jayasundara, Kavisha, Hollis, Aidan, Krahn, Murray, Mamdani, Muhammad, Hoch, Jeffrey S., Grootendorst, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327525/
https://ncbi.nlm.nih.gov/pubmed/30630499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-018-0990-4
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