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Reduced bonobo MHC class I diversity predicts a reduced viral peptide binding ability compared to chimpanzees

BACKGROUND: The highly polymorphic genes of the major histocompatibility complex (MHC) class I are involved in defense against viruses and other intracellular pathogens. Although several studies found reduced MHC class I diversity in bonobos in comparison to the closely related chimpanzee, it is unc...

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Detalhes bibliográficos
Publicado no:BMC Evol Biol
Main Authors: Maibach, Vincent, Vigilant, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327438/
https://ncbi.nlm.nih.gov/pubmed/30630404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-019-1352-0
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