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Detection of endoplasmic reticulum stress and the unfolded protein response in naturally-occurring endocrinopathic equine laminitis

BACKGROUND: Laminitis is often associated with endocrinopathies that cause hyperinsulinemia and is also induced experimentally by hyperinsulinemia, suggesting that insulin initiates laminitis pathogenesis. Hyperinsulinemia is expected to activate pro-growth and anabolic signaling pathways. We hypoth...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Cassimeris, Lynne, Engiles, Julie B., Galantino-Homer, Hannah
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327420/
https://ncbi.nlm.nih.gov/pubmed/30630474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-018-1748-x
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