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Suppression of cathepsin K biomarker in synovial fluid as a free-drug–driven process
Cathepsin K (CatK) inhibitors exhibited chondroprotective and pain-reducing effects in animal models, however, improvements were relatively modest at dose levels achieving maximal suppression of CatK biomarkers in urine. In this report, a previously characterized CatK inhibitor (MK-1256) is utilized...
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| Publicado no: | J Circ Biomark |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6327326/ https://ncbi.nlm.nih.gov/pubmed/30671145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1849454418821819 |
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