Evaluation of Novel 3-Hydroxyflavone Analogues as HDAC Inhibitors against Colorectal Cancer

Alteration of epigenetic enzymes is associated with the pathophysiology of colon cancer with an overexpression of histone deacetylase 8 (HDAC8) enzyme in this tissue. Numerous reports suggest that targeting HDAC8 is a viable strategy for developing new anticancer drugs. Flavonols provide a rich sour...

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Detalhes bibliográficos
Publicado no:Adv Pharmacol Sci
Main Authors: Biswas, Subhankar, Reddy, Neetinkumar D., Jayashree, B. S., Rao, C. Mallikarjuna
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327263/
https://ncbi.nlm.nih.gov/pubmed/30687400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4751806
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