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Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin

Although numerous therapeutic strategies have attempted to target aerobic glycolysis to inhibit tumor progression, these approaches have not resulted in effective clinical outcomes. Murine squamous cell carcinoma (SCC) can be initiated by hair follicle stem cells (HFSCs). HFSCs utilize aerobic glyco...

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Publicat a:Nat Commun
Autors principals: Flores, A., Sandoval-Gonzalez, S., Takahashi, R., Krall, A., Sathe, L., Wei, L., Radu, C., Joly, J. H., Graham, N. A., Christofk, H. R., Lowry, W. E.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327029/
https://ncbi.nlm.nih.gov/pubmed/30626875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07857-9
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