Noradrenergic transmission at alpha1-adrenergic receptors in the ventral periaqueductal gray modulates arousal

BACKGROUND. Dysregulation of arousal is symptomatic of numerous psychiatric disorders. Previous research has shown that the activity of dopamine (DA) neurons in the ventral periaqueductal gray (vPAG) tracks with arousal state, and lesions of vPAG(DA) cells increase sleep. However, the circuitry cont...

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Bibliografiske detaljer
Udgivet i:Biol Psychiatry
Main Authors: Porter-Stransky, Kirsten A., Centanni, Samuel W., Karne, Saumya L., Odil, Lindsay M., Fekir, Sinda, Wong, Jennifer C., Jerome, Canaan, Mitchell, Heather A., Escayg, Andrew, Pederson, Nigel P., Winder, Danny G., Mitrano, Darlene A., Weinshenker, David
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326840/
https://ncbi.nlm.nih.gov/pubmed/30269865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.07.027
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