Potentiation of cerebellar Purkinje cells facilitates whisker reflex adaptation through increased simple spike activity

Cerebellar plasticity underlies motor learning. However, how the cerebellum operates to enable learned changes in motor output is largely unknown. We developed a sensory-driven adaptation protocol for reflexive whisker protraction and recorded Purkinje cell activity from crus 1 and 2 of awake mice....

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Pubblicato in:eLife
Autori principali: Romano, Vincenzo, De Propris, Licia, Bosman, Laurens WJ, Warnaar, Pascal, ten Brinke, Michiel M, Lindeman, Sander, Ju, Chiheng, Velauthapillai, Arthiha, Spanke, Jochen K, Middendorp Guerra, Emily, Hoogland, Tycho M, Negrello, Mario, D'Angelo, Egidio, De Zeeuw, Chris I
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326726/
https://ncbi.nlm.nih.gov/pubmed/30561331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38852
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