Potentiation of cerebellar Purkinje cells facilitates whisker reflex adaptation through increased simple spike activity

Cerebellar plasticity underlies motor learning. However, how the cerebellum operates to enable learned changes in motor output is largely unknown. We developed a sensory-driven adaptation protocol for reflexive whisker protraction and recorded Purkinje cell activity from crus 1 and 2 of awake mice....

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Romano, Vincenzo, De Propris, Licia, Bosman, Laurens WJ, Warnaar, Pascal, ten Brinke, Michiel M, Lindeman, Sander, Ju, Chiheng, Velauthapillai, Arthiha, Spanke, Jochen K, Middendorp Guerra, Emily, Hoogland, Tycho M, Negrello, Mario, D'Angelo, Egidio, De Zeeuw, Chris I
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326726/
https://ncbi.nlm.nih.gov/pubmed/30561331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38852
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