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A stochastic epigenetic Mendelian oligogenic disease model for type 1 diabetes

The incidence of type 1 diabetes (T1D) and some other complex diseases is increasing. The cause has been attributed to an undefined changing environment. We examine the role of the environment (or any changing non-genetic mechanism) in causing the rising incidence, and find much evidence against it:...

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Détails bibliographiques
Publié dans:J Autoimmun
Auteurs principaux: Alper, Chester A., Larsen, Charles E., Trautwein, Michael R., Alford, Dennis R.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326579/
https://ncbi.nlm.nih.gov/pubmed/30309752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2018.09.006
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