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Double-Modified Glycopolymers from Thiolactones to Modulate Lectin Selectivity and Affinity

[Image: see text] Multivalent glycomaterials show high affinity toward lectins but are often nonselective as they lack the precise 3-D presentation found in native glycans. Here, thiolactone chemistry is exploited to enable the synthesis of glycopolymers with both a primary binding (galactose) and a...

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Detalhes bibliográficos
Publicado no:ACS Macro Lett
Main Authors: Wilkins, Laura E., Badi, Nezha, Du Prez, Filip, Gibson, Matthew I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326524/
https://ncbi.nlm.nih.gov/pubmed/30662815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmacrolett.8b00825
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