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Transplantation of Human Intestinal Organoids into the Mouse Mesentery: A More Physiologic and Anatomic Engraftment Site

BACKGROUND: We previously described the development of human intestinal organoids (HIOs) from pluripotent stem cells, as well as their in vivo maturation when transplanted into the mouse kidney capsule. While sufficient for certain aspects of study, this model has limitations. Herein, we describe an...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: Cortez, Alexander R., Poling, Holly M., Brown, Nicole E., Singh, Akaljot, Mahe, Maxime M., Helmrath, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326178/
https://ncbi.nlm.nih.gov/pubmed/30072255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2018.04.048
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