Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children

OBJECTIVES: The objectives of this study were to investigate the population pharmacokinetics of posaconazole in immunocompromised children, evaluate the influence of patient characteristics on posaconazole exposure and perform simulations to recommend optimal starting doses. METHODS: Posaconazole pl...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Boonsathorn, Sophida, Cheng, Iek, Kloprogge, Frank, Alonso, Carlos, Lee, Charmion, Doncheva, Bilyana, Booth, John, Chiesa, Robert, Irwin, Adam, Standing, Joseph F.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326087/
https://ncbi.nlm.nih.gov/pubmed/29679234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0658-1
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