RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives

RANKL/RANK/OPG system consists of three essential signaling molecules: i) the receptor activator of nuclear factor (NF)-kB-ligand (RANKL), ii) the receptor activator of NF-kB (RANK), and iii) the soluble decoy receptor osteoprotegerin (OPG). Although this system is critical for the regulation of ost...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Infante, Marco, Fabi, Alessandra, Cognetti, Francesco, Gorini, Stefania, Caprio, Massimiliano, Fabbri, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325760/
https://ncbi.nlm.nih.gov/pubmed/30621730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-1001-2
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