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Reconstructing the History of Polygenic Scores Using Coalescent Trees
Genome-wide association studies (GWAS) have revealed that many traits are highly polygenic, in that their within-population variance is governed, in part, by small-effect variants at many genetic loci. Standard population-genetic methods for inferring evolutionary history are ill-suited for polygeni...
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| Veröffentlicht in: | Genetics |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325695/ https://ncbi.nlm.nih.gov/pubmed/30389808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301687 |
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