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Evaluation of strategies for the assembly of diverse bacterial genomes using MinION long-read sequencing

BACKGROUND: Short-read sequencing technologies have made microbial genome sequencing cheap and accessible. However, closing genomes is often costly and assembling short reads from genomes that are repetitive and/or have extreme %GC content remains challenging. Long-read, single-molecule sequencing t...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Goldstein, Sarah, Beka, Lidia, Graf, Joerg, Klassen, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325685/
https://ncbi.nlm.nih.gov/pubmed/30626323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5381-7
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