The C677T Polymorphism of the Methylenetetrahydrofolate Reductase Gene and Susceptibility to Late-onset Alzheimer’s Disease

Folate metabolism makes a crucial contribution towards late-onset Alzheimer’s disease (LOAD). Moreover, methylenetetrahydrofolate reductase (MTHFR) constitutes the primary enzyme of the folate pathway. We hypothesize that there is an association of C677T polymorphism in the MTHFR gene with the susce...

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Bibliographic Details
Published in:Open Med (Wars)
Main Authors: Yi, Jian, Xiao, Lan, Zhou, Sheng-Qiang, Zhang, Wen-Jiang, Liu, Bai-Yan
Format: Artigo
Language:Inglês
Published: De Gruyter 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325648/
https://ncbi.nlm.nih.gov/pubmed/30631824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/med-2019-0006
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