Impaired Cognitive Function after Perineuronal Net Degradation in the Medial Prefrontal Cortex

Perineuronal nets (PNNs) are highly organized components of the extracellular matrix that surround a subset of mature neurons in the CNS. These structures play a critical role in regulating neuronal plasticity, particularly during neurodevelopment. Consistent with this role, their presence is associ...

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Veröffentlicht in:eNeuro
Hauptverfasser: Paylor, John W., Wendlandt, Eszter, Freeman, Tara S., Greba, Quentin, Marks, Wendie N., Howland, John G., Winship, Ian R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2018
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New Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325561/
https://ncbi.nlm.nih.gov/pubmed/30627657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0253-18.2018
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