2-Methoxyestradiol improves the apoptosis level in keloid fibroblasts through caspase-dependent mechanisms in vitro

Apoptosis is a form of programmed cell death that occurs in multicellular organisms. Fibroblasts are the main cellular ingredients in keloid tissue, which has a relatively low apoptosis level. A natural metabolite of estradiol, 2-Methoxyestradiol (2ME2) exerts a pro-apoptotic effect on tumor cells....

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Zhang, Ming-Zi, Liu, Yi-Fang, Ding, Ning, Zhao, Peng-Xiang, Zhang, Xin, Liu, Meng-Yu, Adzavon, Yao Mawulikplimi, Huang, Jian-Nan, Long, Xiao, Wang, Xiao-Jun, Wang, You-Bin, Qi, Zheng
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325513/
https://ncbi.nlm.nih.gov/pubmed/30662647
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