Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by Candida albicans Hyphae

Candida albicans is an opportunistic fungal pathogen that can cause life-threatening infections, particularly in immunocompromised patients. C. albicans induced activation of the Nlrp3 inflammasome, leading to secretion of bioactive interleukin 1β (IL-1β) is a crucial myeloid cell immune response ne...

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Bibliographic Details
Published in:mBio
Main Authors: Rogiers, Ona, Frising, Ulrika C., Kucharíková, Soňa, Jabra-Rizk, Mary Ann, van Loo, Geert, Van Dijck, Patrick, Wullaert, Andy
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Observation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325245/
https://ncbi.nlm.nih.gov/pubmed/30622184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02221-18
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