Low Postseroconversion CD4(+) T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection

A positive correlation between virus evolutionary rate and disease progression has been shown for human immunodeficiency virus type 1 (HIV-1) infection. Much less is known about HIV-2, the second causative agent of AIDS. We analyzed 528 HIV-2 env V1-C3 sequences generated from longitudinal plasma sa...

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Udgivet i:mBio
Main Authors: Palm, Angelica A., Lemey, Philippe, Jansson, Marianne, Månsson, Fredrik, Kvist, Anders, Szojka, Zsófia, Biague, Antonio, da Silva, Zacarias José, Rowland-Jones, Sarah L., Norrgren, Hans, Esbjörnsson, Joakim, Medstrand, Patrik
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325243/
https://ncbi.nlm.nih.gov/pubmed/30622192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01245-18
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