Inducible Cell Fusion Permits Use of Competitive Fitness Profiling in the Human Pathogenic Fungus Aspergillus fumigatus

Antifungal agents directed against novel therapeutic targets are required for treating invasive, chronic, and allergic Aspergillus infections. Competitive fitness profiling technologies have been used in a number of bacterial and yeast systems to identify druggable targets; however, the development...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Macdonald, Darel, Thomson, Darren D., Johns, Anna, Contreras Valenzuela, Adriana, Gilsenan, Jane M., Lord, Kathryn M., Bowyer, Paul, Denning, David W., Read, Nick D., Bromley, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325235/
https://ncbi.nlm.nih.gov/pubmed/30397071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01615-18
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