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Rutin Attenuates Vancomycin-Induced Nephrotoxicity by Ameliorating Oxidative Stress, Apoptosis, and Inflammation in Rats

Nephrotoxicity is the major limiting factor for the clinical use of vancomycin (VCM) for treatment of serious infections caused by multiresistant Gram-positive bacteria. This study investigated the renal protective activity of rutin in a rat model of VCM-induced kidney injury in male Wistar rats. VC...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Qu, Shaoqi, Dai, Cunchun, Lang, Fengting, Hu, Longfei, Tang, Qihe, Wang, Haixia, Zhang, Yanping, Hao, Zhihui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325182/
https://ncbi.nlm.nih.gov/pubmed/30397060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01545-18
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