Neoepitope targets of tumour-infiltrating lymphocytes from patients with pancreatic cancer

BACKGROUND: Pancreatic cancer exhibits a poor prognosis and often presents with metastasis at diagnosis. Immunotherapeutic approaches targeting private cancer mutations (neoantigens) are a clinically viable option to improve clinical outcomes. METHODS: 3/40 TIL lines (PanTT26, PanTT39, PanTT77) were...

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Vydáno v:Br J Cancer
Hlavní autoři: Meng, Qingda, Valentini, Davide, Rao, Martin, Moro, Carlos Fernández, Paraschoudi, Georgia, Jäger, Elke, Dodoo, Ernest, Rangelova, Elena, del Chiaro, Marco, Maeurer, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325142/
https://ncbi.nlm.nih.gov/pubmed/30377343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0262-z
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