Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions

Antibodies against the Membrane-Proximal External Region (MPER) of the Env gp41 subunit neutralize HIV-1 with exceptional breadth and potency. Due to the lack of knowledge on the MPER native structure and accessibility, different and exclusive models have been proposed for the molecular mechanism of...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Carravilla, Pablo, Chojnacki, Jakub, Rujas, Edurne, Insausti, Sara, Largo, Eneko, Waithe, Dominic, Apellaniz, Beatriz, Sicard, Taylor, Julien, Jean-Philippe, Eggeling, Christian, Nieva, José L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325134/
https://ncbi.nlm.nih.gov/pubmed/30622256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07962-9
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