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Penalized negative binomial models for modeling an overdispersed count outcome with a high-dimensional predictor space: Application predicting micronuclei frequency

Chromosomal aberrations, such as micronuclei (MN), have served as biomarkers of genotoxic exposure and cancer risk. Guidelines for the process of scoring MN have been presented by the HUman MicroNucleus (HUMN) project. However, these guidelines were developed for assay performance but do not address...

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Udgivet i:PLoS One
Main Authors: Lehman, Rebecca R., Archer, Kellie J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324811/
https://ncbi.nlm.nih.gov/pubmed/30620740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209923
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