Design, Synthesis, and Biological Evaluation of Novel Polyaminocarboxylate Ligand-Based Theranostic Conjugate for Antibody-Targeted Cancer Therapy and Near-Infrared Optical Imaging

We report design, synthesis, and evaluation of polyaminocarboxylate ligand-based antibody conjugate for potential application in targeted cancer therapy and near infrared fluorescent imaging. We synthesized a new polyaminocarboxylate chelate (CAB-NE3TA) as a potential anti-cancer agent. CAB-NE3TA di...

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Foilsithe in:ChemMedChem
Main Authors: Ren, Siyuan, Sun, Xiang, Wang, Haixing, Nguyen, Trung Hai, Sadeghipour, Negar, Xu, Xiaochun, Kang, Chi Soo, Liu, Yujie, Xu, Hua, Wu, Ningjie, Chen, Yanda, Tichauer, Kenneth, Minh, David D. L., Chong, Hyun-Soon
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324731/
https://ncbi.nlm.nih.gov/pubmed/30403833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800598
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