Characterization of Comorbidities Limiting the Recruitment of Patients in Early Phase Clinical Trials

BACKGROUND. Early phase clinical trials evaluate the safety and efficacy of new treatments. The exclusion/inclusion criteria in these trials are usually rigorous and may exclude many patients seen in clinical practice. Our objective was to study the comorbidities limiting the participation of patien...

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Pubblicato in:Oncologist
Autori principali: Duma, Narjust, Kothadia, Sejal M., Azam, Tariq U., Yadav, Siddhartha, Paludo, Jonas, Vera Aguilera, Jesus, Gonzalez Velez, Miguel, Halfdanarson, Thorvardur Ragnar, Molina, Julian R., Hubbard, Joleen M., Go, Ronald S., Mansfield, Aaron S., Adjei, Alex A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2018
Soggetti:
New Drug Development and Clinical Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324635/
https://ncbi.nlm.nih.gov/pubmed/30413668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0687
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