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Long noncoding RNA SNHG16 induces sorafenib resistance in hepatocellular carcinoma cells through sponging miR-140-5p

BACKGROUND: Sorafenib is widely used for treatment of hepatocellular carcinoma (HCC), but the acquired resistance remains a major obstacle for its application. Thus it is of critical importance to elucidate the molecular mechanisms underlying sorafenib resistance in HCC. This study aimed to determin...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Ye, Junfeng, Zhang, Ruoyan, Du, Xiaohong, Chai, Wengang, Zhou, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324603/
https://ncbi.nlm.nih.gov/pubmed/30655679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S175176
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