CXCL12γ Promotes Development of Metastatic Castration Resistant Prostate Cancer by Induction of Cancer Stem Cell and Neuroendocrine Phenotypes

The development of metastatic castration resistant prostate cancer (m-CRPC) poses significant challenges for treatment. Specifically, the emergence of elevated levels of cancer stem cells (CSC) coupled with neuroendocrine (NE) carcinoma behavior is likely to play a critical role in m-CRPC and ultima...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Jung, Younghun, Cackowski, Frank C., Yumoto, Kenji, Decker, Ann M., Wang, Jingcheng, Kim, Jin Koo, Lee, Eunsohl, Wang, Yugang, Chung, Jae-Seung, Gursky, Amy M., Krebsbach, Paul H., Pienta, Kenneth J., Morgan, Todd M., Taichman, Russell S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324566/
https://ncbi.nlm.nih.gov/pubmed/29431639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-2332
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