Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours

BACKGROUND: The risk of recurrence for endocrine-treated breast cancer patients persists for many years or even decades following surgery and apparently successful adjuvant therapy. This period of dormancy and acquired resistance is inherently difficult to investigate; previous efforts have been lim...

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Bibliografiske detaljer
Udgivet i:Breast Cancer Res
Main Authors: Selli, Cigdem, Turnbull, Arran K., Pearce, Dominic A., Li, Ang, Fernando, Anu, Wills, Jimi, Renshaw, Lorna, Thomas, Jeremy S., Dixon, J. Michael, Sims, Andrew H.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323855/
https://ncbi.nlm.nih.gov/pubmed/30616553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1089-5
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