Success of Crizotinib Combined with Whole-Brain Radiotherapy for Brain Metastases in a Patient with Anaplastic Lymphoma Kinase Rearrangement-Positive Non-Small-Cell Lung Cancer

Although crizotinib shows marked antitumor activity in anaplastic lymphoma kinase (ALK) rearrangement-positive non-small-cell lung cancer (NSCLC) patients, all treated patients ultimately develop resistance to this drug. Isolated central nervous system failure without progression at extracranial sit...

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Detalles Bibliográficos
Publicado en:Case Rep Oncol
Autores principales: Okawa, Sachi, Shibayama, Takuo, Shimonishi, Atsushi, Nishimura, Jun, Ozeki, Taichi, Takada, Kenji, Kayatani, Hiroe, Minami, Daisuke, Sato, Ken, Fujiwara, Keiichi, Yonei, Toshiro, Sato, Toshio, Suno, Manabu
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2018
Materias:
Case Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323405/
https://ncbi.nlm.nih.gov/pubmed/30627092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000492150
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