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α-lipoic acid protects against carbon tetrachloride-induced liver cirrhosis through the suppression of the TGF-β/Smad3 pathway and autophagy

α-lipoic acid (ALA) is a naturally occurring antioxidant with protective effects against various hepatic injuries. The aim of the present study was to investigate the mechanisms by which ALA protects the liver from carbon tetrachloride (CCl(4))-induced liver cirrhosis. The widely used liver cirrhosi...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Liu, Guangwei, Liu, Jiangkai, Pian, Linping, Gui, Songlin, Lu, Baoping
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323260/
https://ncbi.nlm.nih.gov/pubmed/30535447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9719
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