Tannic acid, a novel histone acetyltransferase inhibitor, prevents non-alcoholic fatty liver disease both in vivo and in vitro model

OBJECTIVE: We examined the potential of tannic acid (TA) as a novel histone acetyltransferase inhibitor (HATi) and demonstrated that TA prevents non-alcoholic fatty liver disease (NAFLD) by inhibiting HAT activity. METHODS: The anti-HAT activity of TA was examined using HAT activity assays. An in vi...

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Publicat a:Mol Metab
Autors principals: Chung, Min-Yu, Song, Ji-Hye, Lee, Jinhyuk, Shin, Eun Ju, Park, Jae Ho, Lee, Seung-Hyun, Hwang, Jin-Taek, Choi, Hyo-Kyoung
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323241/
https://ncbi.nlm.nih.gov/pubmed/30473486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.11.001
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